"Panther Creek Trail Run":

Directions
From East on I-40 travel through Knoxville and take Exit 394 (Hwy. 11E North). 
This is about 35 miles from the park and Morristown. 

From South on I-81 take Exit 12 (Hwy 160).  Travel North on 160 to Hwy. 11E, turn right and then take the next left.  The park is approximately 2.5 miles on the right.

IIf coming from Gatlinburg, get on I-40 East and take Exit 417 (Hwy. 92).  Travel toward Jefferson City.  At the light, turn right (Hwy. 11E North).  This goes to Morristown and Panther Creek State Park.